urocanic acid

urocanic acid
4-Imidazoleacrylic acid; an acid derived from the oxidative deamination of l-histidine; present in sweat and in dog's urine; elevated levels are observed in cases of urocanate hydratase deficiency. The cis form, resulting from exposure to UV radiation, activates suppressor T cells.

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uro·ca·nic acid .yu̇r-ə-.kā-nik-, -.kan-ik- n a crystalline acid C6H6N2O2 normally present in human skin that is held to act as a screening agent for ultraviolet radiation

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uro·can·ic ac·id (u″ro-kanґik) a product of the direct deamination of histidine, one of the pathways of histidine catabolism; it is accumulated and excreted in the urine in urocanase deficiency.

Medical dictionary. 2011.

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  • Urocanic acid — Chembox new ImageFile=Urocanic acid.svg ImageSize= IUPACName=3 (3 H imidazol 4 yl)prop 2 enoic acid OtherNames= Section1= Chembox Identifiers CASNo=104 98 3 PubChem=1178 SMILES=C1=C(NC=N1)C=CC(=O)O MeSHName=Urocanic+acid Section2= Chembox… …   Wikipedia

  • urocanic acid — noun An intermediate in the catabolism of L histidine, transformed in the liver by urocanate hydratase (or urocanase) into 4 imidazolone 5 propionic acid and subsequently to glutamic acid …   Wiktionary

  • urocanic acid — |yu̇rə|kanik , kānik noun Etymology: ur (I) + canine + ic : a crystalline acid C3H3N2CH . CHCOOH obtained first from the urine of a dog and formed by the enzymic deamination of histidine; 4(or 5) imidazole acrylic acid …   Useful english dictionary

  • urocanic acid — noun Etymology: 1ur + canine + ic; from its being first obtained from the urine of a dog Date: circa 1903 a crystalline acid C6H6N2O2 that is normally present in human skin …   New Collegiate Dictionary

  • urocanic acid — Intermediate in degradation of L histidine …   Dictionary of molecular biology

  • Urocanic aciduria — Infobox Disease Name = PAGENAME Caption = Urocanic acid DiseasesDB = 32605 ICD10 = ICD10|E|70|8|e|70 ICD9 = ICD9|270.5 ICDO = OMIM = 276880 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D014560 Urocanic aciduria, also called urocanate… …   Wikipedia

  • urocanic aciduria — Elevated levels of urocanic acid in the urine …   Medical dictionary

  • Glutamic acid — Glutamic acid …   Wikipedia

  • Oxaloacetic acid — Oxaloacetic acid …   Wikipedia

  • Homogentisic acid — IUPAC name (2,5 Dihydroxyphenyl)acetic acid …   Wikipedia

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