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tro·gli·ta·zone (tro″glĭ-taґzōn) an antihyperglycemic that lowers insulin resistance, formerly used in the treatment of type 2 diabetes mellitus; withdrawn because of hepatotoxicity.Medical dictionary. 2011.
Troglitazone — Systematic (IUPAC) name (RS) 5 (4 [(6 hydroxy 2,5,7,8 tetramethylchroman 2 yl)methoxy]benzyl)thiazolidine 2,4 dione Clinical data Pre … Wikipedia
troglitazone — tro·gli·ta·zone (trōʹglĭ tə zōn ) n. An oral antidiabetic agent that lowers blood glucose by improving the response of target cells to insulin without increasing insulin secretion. [tro , of unknown meaning + gli (ultimately shortening and… … Universalium
troglitazone — noun An antidiabetic and antiinflammatory drug of the thiazolidinedione class … Wiktionary
Тиазолидиндионы — Содержание 1 Механизм действия и эффективность 2 Безопасность … Википедия
Thiazolidinedione — The medication class of thiazolidinedione (also called glitazones) was introduced in the late 1990s as an adjunctive therapy for diabetes mellitus (type 2) and related diseases. Mode of action Thiazolidinediones or TZDs act by binding to PPARs… … Wikipedia
Hepatotoxicity — Alternative names Toxic liver disease Toxin induced liver disease Drug induced liver disease Drug induced liver damage Hepatogenous poisoning Subordinate terms Toxic hepatitis Toxin induced hepatitis Drug induced hepatitis Drug induced hepatic… … Wikipedia
Pioglitazone — Systematic (IUPAC) name (RS) 5 (4 [2 (5 ethylpyridin 2 yl)ethoxy]benzyl)thiazolidine 2,4 dione Clinical data … Wikipedia
Criticism of the Food and Drug Administration — Numerous governmental and non governmental organizations have criticized the U. S. Food and Drug Administration of either over or under regulation. The U.S. Food and Drug Administration (FDA) is an agency of the United States Department of Health … Wikipedia
InnoMed PredTox — Research Project name=InnoMed PredTox title=Innovative Medicines for Europe Predictive Toxicology keywords=Toxicogenomics, Drug development, Pre clinical development fundingAgency=European Commission frameworkProgramme=FP6 projectType=Integrated… … Wikipedia
Anti-diabetic medication — Anti diabetic medications treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral… … Wikipedia
