tretinoin

A keratolytic agent. See retinoic acid.

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tre·tin·o·in tre-'tin-ə-wən n the all-trans isomer of retinoic acid that is applied topically to the skin to treat acne vulgaris and to reduce facial wrinkles, roughness, and pigmented spots and that is administered orally to induce remission of acute myelogenous leukemia in which more than half the cells are malignant promyelocytes called also all-trans-retinoic acid, retinoic acid, vitamin A acid see isotretinoin, retin-a

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n.

a retinoid drug used in the treatment of acne. It is administered topically as a cream, gel, or liquid; side-effects include blistering, altered pigmentation, increased sensitivity to sunlight, and fetal abnormalities. Trade name: Retin-A.

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tret·i·noin (tretґĭ-noin″) all-trans-retinoic acid, applied topically in the treatment of acne vulgaris and as a keratolytic in the treatment of disorders of keratinization, and administered orally as an antineoplastic in the treatment of acute promyelocytic leukemia. Called also retinoic acid and vitamin A acid.