- transamination
- The reaction between an amino acid and an α-keto acid through which the amino group is transferred from the former to the latter; in certain cases the reaction may be between an amino acid and an aldehyde ( e.g., glutamate with glutamate semialdehyde via ornithine transaminase).
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trans·am·i·na·tion .tran(t)s-.am-ə-'nā-shən, .tranz- n a reversible oxidation-reduction reaction in which an amino group is transferred typically from an alpha-amino acid to the carbonyl carbon atom of an alpha-keto acid* * *
n.a process involved in the metabolism of amino acids in which amino groups (-NH2) are transferred from amino acids to certain a-keto acids, with the production of a second keto acid and amino acid. The reaction is catalysed by enzymes (see transaminase), which require pyridoxal phosphate as a coenzyme.* * *
trans·am·i·na·tion (trans″am-ĭ-naґshən) the reversible transfer of an amino group from an amino acid to what was originally an α-keto acid, forming a new keto acid and a new amino acid, without the appearance of ammonia in the free state.
Medical dictionary. 2011.