: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury. There are, not surprisingly, many types of lesions. There are also a number of different ways of classifying and naming lesions. Lesions can, for instance, be categorized according to whether or not they are caused by cancer. A benign lesion is non-cancerous whereas a malignant lesion is cancerous. For example, a biopsy of a skin lesion may prove it to be benign or malignant, or evolving into a malignant lesion (called a premalignant lesion). Lesions can be defined according to the patterns they form. For example, a bull's-eye or target lesion is one that looks like the bull's eye on a target. (In an X-ray of the duodenum, a bull's-eye lesion can represent a tumor with an ulcer (crater) in the center.) A coin lesion is a round shadow resembling a coin on a chest X-ray. It, too, is usually due to a tumor. Lesions can be named for persons who first described them. For instance, a Ghon lesion (or Ghon focus) is the scar-like "signature" in the lungs of adults left by tuberculosis in childhood. Lesions can also be categorized by their size. A gross lesion is one that can be seen with the naked eye. A microscopic or histologic lesion requires the magnification of a microscope to be seen. The basis of sickle cell disease is a molecular lesion, one that is not even visible with a microscope but is only detectable on the molecular (protein or DNA) level. Location is another basis for naming lesions. In neurology, a central lesion involves the brain or spinal cord, i.e., the central nervous system. A peripheral lesion involves the nerves away from the spinal cord and does not involve the central nervous system. There is a virtually endless assortment of lesions in medicine: primary lesions, secondary lesions, impaction lesions, indiscriminate lesions, irritative lesions, etc. Many are named for people including the Armanni-Ebstein lesion, a Bankart lesion, a Blumenthal lesion, and so on. The word "lesion" comes from the Latin noun "laesio" meaning "an attack or injury" which is related in Latin to the verb "laedere" = "to hurt, strike or wound."
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1. A wound or injury. 2. A pathologic change in the tissues. 3. One of the individual points or patches of a multifocal disease. [L. laedo, pp. laesus, to injure]
- Baehr-Lohlein l. SYN: Lohlein-Baehr l..
- Bankart l. a tear of the anterior glenoid labrum accompanying detachment of the inferior glenohumeral ligament.
- benign lymphoepithelial l. benign tumor-like masses of lymphoid tissue in the parotid gland, containing scattered small, mainly solid islands of epithelial cells. SYN: Godwin tumor.
- Bracht-Wächter l. a focal collection of lymphocytes and mononuclear cells within the myocardium in bacterial endocarditis.
- caviar l. a dilated vein or varicule existing in the venous collecting system under the tongue.
- coin l. of lungs SYN: nodular opacity.
- Dieulafoy l. an abnormally large submucosal artery located in the proximal stomach that may be the site of acute and recurrent episodes of massive hemorrhage.
- Duret l. small hemorrhage(s) in the floor of the fourth ventricle or beneath the aqueduct of Sylvius.
- Ghon primary l. SYN: Ghon tubercle.
- gross l. a l. plainly visible to the naked eye.
- high-grade squamous intraepithelial l. (HSIL, HGSIL) term used in the Bethesda system for reporting cervical/vaginal cytologic diagnosis to describe a spectrum of noninvasive cervical epithelial abnormalities, including moderate and severe dysplasia, carcinoma in situ, and cervical intraepithelial neoplasia grades 2 and 3. SEE ALSO: Bethesda system, ASCUS, atypical glandular cells of undetermined significance, under cell, low-grade squamous intraepithelial l..
- Hill-Sachs l. an irregularity seen in the head of the humerus following anterior dislocation of the shoulder; caused by impaction of posterolateral portion of the head of the humerus against the anterior edge of the glenoid.
- Janeway l. one of the stigmata of infectious endocarditis : irregular, erythematous, flat, painless macules on the palms, soles, thenar and hypothenar eminences of the hands, tips of the fingers, and plantar surfaces of the toes; rarely a diffuse rash. In acute endocarditis the lesions may be hemorrhagic or purple.
- Lohlein-Baehr l. focal embolic glomerulonephritis occurring in bacterial endocarditis. SYN: Baehr-Lohlein l..
- lower motor neuron l. injury to motor cells in the brainstem or spinal cord, or of the axons derived from them.
- low-grade squamous intraepithelial l. (LGSIL, LSIL) term used in the Bethesda system for reporting cervical/vaginal cytologic diagnosis to describe a spectrum of noninvasive cervical epithelial abnormalities; these lesions include the cellular changes associated with human papilloma virus cytopathologic effect and mild dysplasia (cervical intraepithelial neoplasia grade 1). SEE ALSO: Bethesda system, reactive changes, under change, ASCUS, atypical glandular cells of undetermined significance, under cell.
- Mallory-Weiss l. SYN: Mallory-Weiss syndrome.
- precancerous l. a noninvasive l. with a predictable likelihood of becoming malignant; e.g., actinic keratosis.
- radial sclerosing l. a variant of sclerosing adenosis of the breast with central scar formation and radiating hyperplastic ducts. SYN: radial scar.
- ring-wall l. a small ring hemorrhage in the brain that stimulates proliferation of a glial ring.
- supranuclear l. injury to cerebral descending (corticonuclear) fibers above the brainstem or spinal motor nerve nucleus. SYN: upper motor neuron l..
- upper motor neuron l. SYN: supranuclear l..
- wire-loop l. thickening of the basement membrane, with fibrinoid staining, of scattered peripheral capillaries in renal glomeruli; characteristic of renal involvement in systemic lupus erythematosus; the appearance of an affected capillary wall resembles a loop used in microbiology.

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le·sion 'lē-zhən n an abnormal change in structure of an organ or part due to injury or disease esp one that is circumscribed and well defined
le·sioned -zhənd adj
lesion vt to produce lesions in (as an animal's brain)

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a zone of tissue with impaired function as a result of damage by disease or wounding. Apart from direct physical injury, examples of primary lesions include abscesses, ulcers, and tumours; secondary lesions (such as crusts and scars) are derived from primary ones.

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le·sion (leґzhən) [L. laesio; laedere to hurt] any pathological or traumatic discontinuity of tissue or loss of function of a part.

Medical dictionary. 2011.

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  • lésion — [ lezjɔ̃ ] n. f. • 1160; lat. læsio, de lædere « léser » 1 ♦ Dr. Atteinte portée aux intérêts de qqn. ⇒ dommage, préjudice, tort. Spécialt (dans un contrat) Préjudice matériel qui résulte, pour une partie exploitée par l autre partie, de l… …   Encyclopédie Universelle

  • Lesion — Lésion Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Suivant les contextes, le terme lésion peut désigner différente choses : En médecine, une lésion désigne une partie d un organe se trouvant… …   Wikipédia en Français

  • lesión — f. patol. Alteración o daño producido en la estructura o función de un tejido u órgano. Medical Dictionary. 2011. lesión daño o …   Diccionario médico

  • lesion — Lesion. s. f. Tort, dommage qu on souffre en quelque transaction, en quelque marché. Il y a lesion d outre moitié de juste prix. il ne peut pas souffrir cette lesion sans s en plaindre. montrez moy en quoy il y a lesion, où est la lesion …   Dictionnaire de l'Académie française

  • lesion — le·sion / lē zhən/ n [Anglo French, damage, injury, from Latin laesio, from laedere to injure] in the civil law of Louisiana: loss from failure to receive a threshold amount or value (as one half market value) for immovable property conveyed or… …   Law dictionary

  • lesion — (n.) early 15c., from M.Fr. lesion, from L. laesionem (nom. laesio) injury, from pp. stem of laedere to strike, hurt, damage, of unknown origin. Originally with reference to any sort of hurt, whether physical or not …   Etymology dictionary

  • lesión — sustantivo femenino 1. Alteración de un tejido orgánico por una enfermedad o traumatismo: En la pelea sufrí lesiones de diversa consideración. La enfermedad le ha causado graves lesiones en los pies. 2. Daño o perjuicio en general: Las calumnias… …   Diccionario Salamanca de la Lengua Española

  • Lesion — Le sion (l[=e] zh[u^]n), n. [F. l[ e]sion, L. laesio, fr. laedere, laesum, to hurt, injure.] A hurt; an injury. Specifically: (a) (Civil Law) Loss sustained from failure to fulfill a bargain or contract. Burrill. (b) (Med.) Any morbid change in… …   The Collaborative International Dictionary of English

  • lesion — *wound, trauma, traumatism, bruise, contusion Analogous words: *injury, hurt, damage …   New Dictionary of Synonyms

  • lesion — [n] injury, wound abrasion, bruise, contusion, cut, gash, laceration, scrape, scratch, sore; concept 309 …   New thesaurus

  • lesión — (Del lat. laesĭo, ōnis). 1. f. Daño o detrimento corporal causado por una herida, un golpe o una enfermedad. 2. Daño, perjuicio o detrimento. 3. Der. Daño que se causa en las ventas por no hacerlas en su justo precio. 4. Der. Perjuicio sufrido… …   Diccionario de la lengua española

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