splenomegaly, splenomegalia

Enlargement of the spleen. SYN: megalosplenia. [spleno- + G. megas (megal-), large]

- congestive s. enlargement of the spleen due to passive congestion; sometimes used as a synonym for Banti syndrome.

- Egyptian s. term sometimes used as a synonym for schistosomiasis mansoni, although hepatomegaly and fibrosis are more consistently found than is an enlarged spleen.

- hemolytic s. s. associated with hemolytic jaundice.

- hyperreactive malarious s. a syndrome characterized by persistent s., exceptionally high serum IgM and malaria antibody levels, and hepatic sinusoidal lymphocytosis; believed to be a disturbance in the T-lymphocyte control of the humoral response to recurrent malaria. SYN: tropical s. syndrome.

- Niemann s. enlargement of spleen occurring in Niemann-Pick disease.

- tropical s. SYN: visceral leishmaniasis.