- nodular p. probably a form of subacute sclerosing p.. SYN: Pette-Döring disease.
- subacute sclerosing p. (SSPE) a rare chronic, progressive encephalitis that affects primarily children and young adults, caused by the measles virus. Characterized by a history of primary measles infection before the age of 2 years, followed by several asymptomatic years, and then gradual, progressive psychoneurological deterioration, consisting of personality change, seizures, myoclonus, ataxia, photosensitivity, ocular abnormalities, spasticity, and coma. Characteristic periodic activity is seen on EEG; pathologically, the white matter of both the hemispheres and brainstem are affected, as well as the cerebral cortex, and eosinophilic inclusion bodies are present in the cytoplasm nuclei of neurons and glial cells. Death usually occurs within 3 years. SYN: Bosin disease, Dawson encephalitis, inclusion body encephalitis, sclerosing leukoencephalitis, subacute inclusion body encephalitis, subacute sclerosing leukoencephalitis, van Bogaert encephalitis.

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pan·en·ceph·a·li·tis .pan-in-.sef-ə-'līt-əs n, pl -lit·i·des -'lit-ə-.dēz inflammation of the brain affecting both white and gray matter see SUBACUTE SCLEROSING PANENCEPHALITIS

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pan·en·ceph·a·li·tis (pan″ən-sef″ə-liґtis) a type of encephalitis, probably of viral origin, that produces intranuclear or intracytoplasmic inclusion bodies that cause parenchymatous lesions in both gray and white matter of the brain.

Medical dictionary. 2011.

Look at other dictionaries:

  • panencephalitis — noun diffuse inflammation of the entire brain • Hypernyms: ↑encephalitis, ↑cephalitis, ↑phrenitis • Hyponyms: ↑subacute sclerosing panencephalitis, ↑SSPE, ↑inclusion body encephalitis, ↑ …   Useful english dictionary

  • panencephalitis — pan·en·ceph·a·li·tis (păn ĕn sĕf ə līʹtĭs) n. 1. Encephalitis that affects both gray and white matter of the brain, resulting in progressive loss of mental and motor functions. 2. Subacute sclerosing panencephalitis. * * * …   Universalium

  • panencephalitis — n. disease that is believed to be caused by a virus that attacks the brain and causes lesions …   English contemporary dictionary

  • panencephalitis — pan·encephalitis …   English syllables

  • Panencephalitis, subacute sclerosing (SSPE) — A chronic brain disease of children and adolescents that occurs months to often years after an attack of measles, causing convulsions, motor abnormalities, mental retardation and, usually, death …   Medical dictionary

  • Subacute sclerosing panencephalitis — Classification and external resources ICD 10 A81.1 ICD 9 046.2 …   Wikipedia

  • subacute sclerosing panencephalitis — noun a rare chronic progressive encephalitis caused by the measles virus and occurring primarily in children and young adults; death usually occurs within three years; characterized by primary measles infection before the age of two years • Syn:… …   Useful english dictionary

  • subacute sclerosing panencephalitis — noun Etymology: panencephalitis from New Latin, from pan + encephalitis Date: 1950 a usually fatal neurological disease of children and young adults caused by infection of the brain by a previously latent measles virus that is marked especially… …   New Collegiate Dictionary

  • subacutesclerosing panencephalitis — subacute scle·ros·ing panencephalitis (sklə rōʹsĭng) n. An often fatal degenerative disease of the central nervous system occurring chiefly in young people, caused by slow infection with a measles virus and characterized by progressive loss of… …   Universalium

  • subacute sclerosing panencephalitis — n a usu. fatal neurological disease of children and young adults that is caused by infection of the brain by a previously latent morbillivirus causing measles and that is marked esp. by behavioral changes, myoclonic seizures, progressive… …   Medical dictionary

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