MPTP

MPTP
Piperidine derivative which causes irreversible symptoms of parkinsonism in humans and monkeys. A by-product of illicitly manufactured meperidine that caused numerous cases of parkinsonism. Used as an experimental tool in research on parkinsonism.
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1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyridine; mitochondrial permeability transition pore

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MPTP .em-(.)pē-(.)tē-'pē n [1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine] a neurotoxin C12H15N that destroys dopamine-producing neurons of the substantia nigra and causes symptoms (as tremors and rigidity) similar to those of Parkinson's disease

Medical dictionary. 2011.

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  • MPTP — Général Nom IUPAC 1 Méthyl 4 phényl 1,2,3,6 tétrahydropyridine No CAS …   Wikipédia en Français

  • MPTP — son las siglas de la neurotoxina 1 metil 4 fenil 1,2,3,6 tetrahidropiridina, un compuesto secundario que se forma a partir de la síntesis de meteridina o heroína sintética. La ingestión de MPTP conlleva a la destrucción de neuronas en la… …   Wikipedia Español

  • MPTP — [Abk. für 1 Methyl 4 phenyl 1,2,3,6 tetrahydropyridin]: mit sog. Designerdrogen verwandtes, Parkinsonismus hervorrufendes Neurotoxin …   Universal-Lexikon

  • MPTP — This article is about the chemical. For the mitochondrial pore, see mitochondrial permeability transition. MPTP IUPAC name …   Wikipedia

  • MPTP — Strukturformel Allgemeines Name MPTP Andere Namen 1 Methyl 4 ph …   Deutsch Wikipedia

  • MPTP — noun a) A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users. b) A neurotoxin which degrades into MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the… …   Wiktionary

  • MPTP — Main Propulsion Test Program NASA Weltraumfahrt …   Acronyms

  • MPTP — Main Propulsion Test Program ( > NASA Acronym List ) {Weltraumfahrt} …   Acronyms von A bis Z

  • MPTP — abbr. med. analog of meperidine (used by drug addicts) – аналог меперидина, используемый наркоманами …   Dictionary of English abbreviation

  • MPTP — abbr. methyl 4 phenyl 1,2,3,6 tetrahydropyridine …   Dictionary of abbreviations

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