- motilin
- A 22-amino acid polypeptide occurring in duodenal mucosa as a controller of normal gastrointestinal motor activity; in minute (ng) doses it induces powerful motor activity increases in the fundic gland area and antral pouches of the stomach, with an increase in pepsin output from the former. [motility + -in]
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mo·til·in mō-'til-ən n a polypeptide hormone secreted by the small intestine that increases gastrointestinal motility and stimulates the production of pepsin* * *
mo·til·in (mo-tilґin) a polypeptide hormone (2698 daltons, 22 amino acids) secreted by the enterochromaffin cells of the intestine; it increases motility of several portions of the gastrointestinal tract and stimulates pepsin secretion. Its release is stimulated by the presence of acid or fat in the duodenum; its physiologic role in gastrointestinal function is not yet known.
Medical dictionary. 2011.