mibefradil

mibefradil
A tetralol derivative in a new class of calcium antagonists that block at T-type channels; used to treat mild to moderate hypertension and angina pectoris.

Medical dictionary. 2011.

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  • Mibefradil — Systematic (IUPAC) name (1S,2S) 2 (2 ((3 (1H benzo[d]imidazol 2 yl)propyl) (methyl)amino)ethyl) 6 fluoro 1 isopropyl 1,2,3,4 tetrahydronaphthalen 2 yl 2 methoxyacetate Clinic …   Wikipedia

  • mibefradil — noun A particular calcium channel blocker used to treat hypertension and chronic angina pectoris …   Wiktionary

  • Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels.[1] CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel …   Wikipedia

  • Verapamil — Systematic (IUPAC) name (RS) 2 (3,4 dimethoxyphenyl) 5 {[2 (3,4 dimethoxyphenyl)ethyl] (methyl)amino} 2 prop 2 ylpentanenitrile Clinical data Licence …   Wikipedia

  • Amlodipine — Systematic (IUPAC) name …   Wikipedia

  • Nifedipine — Systematic (IUPAC) name 3,5 dimethyl 2,6 dim …   Wikipedia

  • Diltiazem — Systematic (IUPAC) name cis (+) [2 (2 dimethylaminoethyl) 5 (4 methoxyphenyl) 3 oxo 6 thia 2 azabicyclo[5.4.0]undeca 7,9, 11 trien 4 yl]ethanoate …   Wikipedia

  • ATC code C08 — A section of the Anatomical Therapeutic Chemical Classification System.C Cardiovascular system =C08C Selective calcium channel blockers with mainly vascular effects= C08CA Dihydropyridine derivatives:C08CA01 Amlodipine:C08CA02 Felodipine:C08CA03… …   Wikipedia

  • CYP3A4 — Cytochrome P450, family 3, subfamily A, polypeptide 4 Structure of CYP3A4 (from PDB 1W0E). Heme group visible at center …   Wikipedia

  • CYP2D6 — Cytochrome P450, family 2, subfamily D, polypeptide 6 PDB rendering based on 2f9q …   Wikipedia

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