macroglobulinemia

macroglobulinemia
The presence of increased levels of macroglobulins in the circulating blood.
- Waldenström m. m. occurring in elderly persons, characterized by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anemia, increased sedimentation rate, and hyperglobulinemia with a narrow peak in γ-globulin or β2-globulin at about 19 S units. The spleen, liver, or lymph node s are often enlarged and there is frequently purpura or mucosal bleeding. SYN: hyperglobulinemic purpura, Waldenström purpura, Waldenström syndrome.

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mac·ro·glob·u·lin·emia or chiefly Brit mac·ro·glob·u·lin·ae·mia -.gläb-yə-lə-'nē-mē-ə n a disorder characterized by increased blood serum viscosity and the presence of macroglobulins in the serum
mac·ro·glob·u·lin·emic or chiefly Brit mac·ro·glob·u·lin·ae·mic -mik adj

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mac·ro·glob·u·lin·emia (mak″ro-glob″u-lĭ-neґme-ə) [macroglobulin + -emia] a condition characterized by increased macroglobulins in the blood.

Medical dictionary. 2011.

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  • macroglobulinemia de Waldenström — f. hemat. Macroglobulinemia que afecta principalmente a varones ancianos ocasionada por una proliferación clonal de linfocitos B que segregan grandes cantidades de IgM. Los síntomas que provoca son astenia, debilidad, alteraciones visuales,… …   Diccionario médico

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  • Macroglobulinemia, Waldenstrom — A chronic low grade (indolent) type of lymphoma due to a malignant clone of plasma cells. These plasma cells multiply out of control, invade the bone marrow, lymph nodes, and spleen, and characteristically produce huge amounts of a large sized… …   Medical dictionary

  • macroglobulinemia de Waldenström — Eng. Waldenström s macroglobulinemia Síndrome de hiperviscosidad que cursa con paraproteinemia y presencia a nivel retiniano de dilatación venosa, segmentación y tortuosidad vascular, hemorragias retinianas superficiales y profundas, exudados… …   Diccionario de oftalmología

  • macroglobulinemia — noun Etymology: New Latin Date: 1949 a disorder characterized by increased blood serum viscosity and the presence of macroglobulins in the serum • macroglobulinemic adjective …   New Collegiate Dictionary

  • macroglobulinemia — mac·ro·glob·u·lin·e·mi·a (măk rō glŏb yə lə nēʹmē ə) n. A condition marked by an abnormally high concentration of macroglobulins in the blood serum. * * * …   Universalium

  • macroglobulinemia — noun The presence of high levels of macroglobulins in the blood …   Wiktionary

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