- l. hydroxylase an enzyme that acts on specific l. residues in certain proteins ( E.G., collagens) with α-ketoglutarate and O2 to produce δ-hydroxylysyl residues, succinate, and CO2; this enzyme, which requires Fe2+ and ascorbate, is deficient in Ehlers-Danlos syndrome type VI. SYN: l. 2-oxoglutarate dioxygenase.
- l. oxidase an enzyme, which requires Cu2+ and O2, that oxidizes certain l. residues in collagen to allysyl residues and hydroxylysyl residues to hydroxyallysyl residues; this is a required step for the cross-linking (via aldol condensations and Amadori rearrangements) of collagen strands; a lower activity of this enzyme is associated with occipital horn syndrome.
- l. 2-oxoglutarate dioxygenase SYN: l. hydroxylase.

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ly·syl 'lī-səl n the amino acid radical or residue H2N(CH2)4CH(NH2)CO- of lysine abbr. Lys

* * *

ly·syl (liґsəl) the acyl radical of lysine.

Medical dictionary. 2011.

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  • lysyl- — lizil statusas T sritis chemija apibrėžtis Grupė. formulė H₂N(CH₂)₄CH(NH₂)CO– atitikmenys: angl. lysyl rus. лизил ryšiai: sinonimas – 2,6 diaminoheksanoil …   Chemijos terminų aiškinamasis žodynas

  • Lysyl oxidase — Lysyl oxidase, also known as LOX, is a human gene.cite web | title = Entrez Gene: LOX lysyl oxidase| url = Cmd=ShowDetailView TermToSearch=4015| accessdate = ] PBB Summary section title = summary… …   Wikipedia

  • lysyl hydroxylase — lysyl hydroxylase. См. лизилгидроксилаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Lysyl hydroxylase — protein Name = procollagen lysine 1, 2 oxoglutarate 5 dioxygenase 1 caption = width = HGNCid = 9081 Symbol = PLOD1 AltSymbols = LLH, PLOD EntrezGene = 5351 OMIM = 153454 RefSeq = NM 000302 UniProt = Q02809 PDB = ECnumber = Chromosome =… …   Wikipedia

  • Lysyl oxydase — Oxydase Une oxydase est une enzyme catalysant une réaction d oxydo réduction impliquant une molécule de dioxygène (O2) comme électron accepteur. Dans ces réactions, l oxygène est réduit en eau (H2O) ou en peroxyde d hydrogène (H2O2). Les oxydases …   Wikipédia en Français

  • lysyl oxidase — Extracellular enzyme that deaminates lysine and hydroxylysine residues in collagen or elastin to form aldehydes, that then interact with each other or with other lysyl side chains to form crosslinks …   Dictionary of molecular biology

  • lysyl — adjective Of or pertaining to lysine …   Wiktionary

  • lysyl — ly·syl …   English syllables

  • lysyl — ˈlīsə̇l noun ( s) Etymology: lysine + yl : the acid radical H2N(CH2)4CH(NH2)CO2− of lysine …   Useful english dictionary

  • lysyl-bradykinin — SYN: kallidin. * * * kallidin …   Medical dictionary

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