lipogranulomatosis

lipogranulomatosis
1. Presence of lipogranulomas. 2. Local inflammatory reaction to necrosis of adipose tissue.
- disseminated l. a form of mucolipodosis, developing soon after birth because of deficiency of ceramidase; characterized by swollen joints, subcutaneous nodules, lymphadenopathy, and accumulation in lysosomes of affected cells of PAS-positive lipid consisting of ceramide. SYN: Farber disease, Farber syndrome.

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n.
an abnormality of lipid metabolism causing deposition of yellowish nodules in the skin.

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lipo·gran·u·lo·ma·to·sis (lip″o-gran″u-lo-mə-toґsis) a condition of faulty lipid metabolism in which yellow nodules of lipoid matter are deposited in the skin and mucosae, giving rise to granulomatous reactions.

Medical dictionary. 2011.

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