isoimmunization

Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species; e.g., i. is likely to occur when an Rh-negative person is treated with a transfusion of Rh-positive blood from another human being, or an Rh-negative woman has a pregnancy in which the fetus inherits Rh-positive red blood cells.

* * *

iso·im·mu·ni·za·tion or chiefly Brit iso·im·mu·ni·sa·tion .ī-sō-.im-yə-nə-'zā-shən n production by an individual of antibodies against constituents of the tissues of another individual of the same species (as when transfused with blood from one belonging to a different blood group)

* * *

n.

the development of antibodies (isoantibodies) within an individual against antigens from another individual of the same species.

* * *

iso·im·mu·ni·za·tion (i″so-im″u-nĭ-zaґshən) development of antibodies against an antigen derived from a genetically dissimilar individual of the same species; see also isoantigen.