Duodenal ulcer

Duodenal ulcer
An ulcer (a hole in the lining) of the duodenum (the first portion of the small intestine). Ulcers can affect the stomach, duodenum, or esophagus. Their formation is related to H. pyloridus bacteria in the stomach, anti-inflammatory medications, and smoking cigarettes. Ulcer pain may not correlate with the presence or severity of ulceration. Diagnosis is made with barium x-ray or endoscopy. Complications of ulcers include bleeding, perforation, and blockage of the stomach (gastric obstruction). Treatment involves antibiotics to eradicate H. pyloridus, eliminating risk factors, and preventing complications.

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duodenal ulcer n a peptic ulcer situated in the duodenum

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an ulcer in the duodenum, caused by the action of acid and pepsin on the duodenal lining (mucosa) of a susceptible individual. It is usually associated with an increased output of stomach acid. Infection of the antrum of the stomach with Helicobacter is almost always present. Symptoms include pain in the upper abdomen, especially when the stomach is empty, which often disappears completely for weeks or months; vomiting may occur. Complications include bleeding (see haematemesis), perforation, and obstruction due to scarring (see pyloric stenosis). Symptoms are relieved by antacid medicines; most ulcers heal if treated by an antisecretory drug, or if H. pylori is eradicated by a combination of a proton-pump inhibitor (or an H2-receptor antagonist) and antibiotics. Surgery (see gastrectomy, <

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a peptic ulcer in the duodenum.

Medical dictionary. 2011.

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