γ-glutamylcysteine

γ-glutamylcysteine
A necessary precursor in the biosynthesis of glutathione; contains an isopeptide rather than a eupeptide bond.
- γ-glutamylcysteine synthetase an enzyme that catalyzes the first step in glutathione biosynthesis, reacting l-glutamate, l-cysteine, and ATP to form γ-glutamylcysteine, ADP, and orthophosphate; inhibited by thiols such as glutathione.

Medical dictionary. 2011.

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