γ-glutamylcysteine

γ-glutamylcysteine
A necessary precursor in the biosynthesis of glutathione; contains an isopeptide rather than a eupeptide bond.
- γ-glutamylcysteine synthetase an enzyme that catalyzes the first step in glutathione biosynthesis, reacting l-glutamate, l-cysteine, and ATP to form γ-glutamylcysteine, ADP, and orthophosphate; inhibited by thiols such as glutathione.

Medical dictionary. 2011.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • glutamylcysteine — noun A dipeptide derived from glutamic acid and cysteine …   Wiktionary

  • Gamma-glutamylcysteine synthetase — (EC 6.3.2.2) (glutamate cysteine ligase, GCL) is the first enzyme in the glutathione biosynthesis pathway. FunctionIt catalyses the ATP dependent condensation of cysteine and glutamate to form the dipeptide gamma glutamylcysteine. The peptide… …   Wikipedia

  • Gamma-Glutamylcysteine — chembox new ImageFile=gamma Glutamylcysteine.svg ImageSize= IUPACName= OtherNames= Section1=Chembox Identifiers CASNo= PubChem=842 SMILES=C(CC(=O)NC(CS)C(=O)O)C(C(=O)O)N MeSHName=Gamma glutamylcysteine Section2=Chembox Properties… …   Wikipedia

  • gamma-glutamylcystéine — γ glutamylcystéine Structure de la L γ glutamyl L cystéine Général Synonymes …   Wikipédia en Français

  • γ-glutamylcysteine synthetase deficiency — γ glu·ta·myl·cys·te·ine syn·the·tase de·fi·cien·cy (gloo″tə məl sisґte ēn sinґthə tās) an autosomal recessive aminoacidopathy of glutathione synthesis caused by mutation in the GCLC gene (locus: 6p12), which… …   Medical dictionary

  • [computer-assisted surgery]; glucocorticosteroid; glutamylcysteine synthetase; glycine cleavage system — Gross cell surface antigen …   Medical dictionary

  • γ-glutamylcysteine — γ glu·ta·myl·cys·te·ine (gloo″tə məl sisґte ēn) glutamate linked via its γ carboxyl group to the amino group of cysteine; it is an intermediate in the synthesis of glutathione …   Medical dictionary

  • γ-glutamylcysteine synthetase — γ glu·ta·myl·cys·te·ine syn·the·tase (gloo″tə məl sisґte ēn sinґthə tās) glutamate cysteine ligase …   Medical dictionary

  • GLCLC — glutamylcysteine synthase …   Medical dictionary

  • GLCLC — • glutamylcysteine synthase …   Dictionary of medical acronyms & abbreviations

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”