gephyrin

gephyrin
A protein in the ataxia telangiectasia mutation–related family, essential for glycine receptor clustering on neuronal membranes.

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ge·phyr·in (jə-firґin) a peripheral membrane protein associated with the cytoplasmic domain of neuronal glycine receptors; it binds microtubules and is necessary for the clustering of glycine receptors.

Medical dictionary. 2011.

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  • Gephyrin — is a protein that is a component of the postsynaptic protein network of inhibitory synapses. Positive antibody staining for gephyrin at a synapse is consistent with the presence of glycine and/or GABA A receptors. Gephyrin displaces GABA… …   Wikipedia

  • gephyrin — Peripheral membrane protein of the cytoplasmic face of the glycinergic synapses in the spinal cord. Appears at developing postsynaptic sites before the glycine receptor and may therefore be important in clustering. Thought to interact with the… …   Dictionary of molecular biology

  • gephyrin — noun A protein associated with synapses …   Wiktionary

  • GPHN — Gephyrin, also known as GPHN, is a human gene.cite web | title = Entrez Gene: GPHN gephyrin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10243| accessdate = ] PBB Summary section title = summary text =… …   Wikipedia

  • Collybistin — is a protein much like gephyrin which is thought to aid the formation of submembrane gephyrin aggregates that accumulate hetero oligomeric glycine receptors. Data from Nature Neuroscience 2000 suggests that the expression of collybistin regulates …   Wikipedia

  • ARHGEF9 — Cdc42 guanine nucleotide exchange factor (GEF) 9, also known as ARHGEF9, is a human gene.cite web | title = Entrez Gene: ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

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  • GLRB — Glycine receptor, beta, also known as GLRB, is a human gene.cite web | title = Entrez Gene: GLRB glycine receptor, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2743| accessdate = ] PBB Summary… …   Wikipedia

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