gastrinoma

A gastrin-secreting tumor associated with the Zollinger-Ellison syndrome.

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gas·tri·no·ma .gas-trə-'nō-mə n, pl -mas also -ma·ta -mət-ə a tumor that often involves blood vessels, usu. occurs in the pancreas or the wall of the duodenum, and produces excessive amounts of gastrin which stimulates gastric-acid secretion and consequent formation of ulcers esp. in the duodenum and the jejunum see ZOLLINGER-ELLISON SYNDROME

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n.

a rare tumour that secretes excess amounts of the hormone gastrin, causing the Zollinger-Ellison syndrome. Such tumours most frequently occur in the pancreas; about half of them are malignant.

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gas·tri·no·ma (gas″trĭ-noґmə) a tumor that secretes gastrin. Most are islet cell tumors of cells other than the beta cells; some are found at sites such as the antrum of the stomach, the hilum of the spleen, or regional lymph nodes. This is the usual cause of Zollinger-Ellison syndrome.