elastase

elastase
A serine proteinase hydrolyzing elastin; other e.-like enzymes have been identified ( e.g., pancreatic e. [pancreatopeptidase E] and leukocyte e. [lysosomal or neutrophil e.]) with different sequences and kinetic parameters; all have fairly broad specificities.

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elas·tase i-'las-.tās, -.tāz n an enzyme esp. of pancreatic juice that digests elastin

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elas·tase (e-lasґtās) any of a group of serine endopeptidases secreted by neutrophils, macrophages, mast cells, the pancreas, and certain bacteria; they catalyze the cleavage of elastin and other proteins, preferentially cutting polypeptide chains at bonds involving the carbonyl groups of amino acids. Elastase activity is specifically inhibited by alpha1-antitrypsin. See also leukocyte elastase and pancreatic elastase II.

Medical dictionary. 2011.

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  • elastase — noun Etymology: elastin + ase Date: 1949 an enzyme especially of pancreatic juice that digests elastin …   New Collegiate Dictionary

  • elastase — Serine protease that will digest elastin and collagen Type IV; inhibited by alpha 1 protease inhibitor of plasma …   Dictionary of molecular biology

  • elastase — /i las tays, taz/, n. Biochem. a pancreatic protease that catalyzes the hydrolysis of elastin and other related proteins to polypeptides and amino acids. [1945 50; ELAST(IN) + ASE] * * * …   Universalium

  • elastase — noun An endopeptidase enzyme involved in the breakdown of elastin …   Wiktionary

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  • Elastase — E|las|ta|se [Kurzw. aus ↑ Elastin u. ↑ ase], die; , n; Syn.: Pankreatopeptidase E: eine Proteinase aus der Bauchspeicheldrüse, die Peptidbindungen insbes. des Elastins spaltet. * * * Elas|ta|se , die; , n [zu ↑ elastisch u. ase = Suffix zur Bez.… …   Universal-Lexikon

  • Elastase — Elasta̱se [Kurzw. aus elastisch u. ↑...ase] w; , n: Enzym, das die Kittsubstanzen der elastischen Muskelfasern abbaut …   Das Wörterbuch medizinischer Fachausdrücke

  • Elastase — Elas|ta|se* [ela...] die; , n Kurzw. aus ↑elastisch u. ↑...ase> Enzym, das die Kittsubstanzen der elastischen Muskelfasern abbaut (Biochem.) …   Das große Fremdwörterbuch

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