A class of basic antibiotic polypeptides, found in neutrophils, that kill bacteria by causing membrane damage. These cytotoxic peptides contain 29–38 amino acid residues. [L. de-fendo, pp. de-fensum, to repel, avert, + -in]

Medical dictionary. 2011.

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  • defensins — Family of small (30 35 residue) cysteine rich cationic proteins found in vertebrate phagocytes (notably the azurophil granules of neutrophils) and active against bacteria, fungi and enveloped viruses. May constitute up to 5% of the total protein …   Dictionary of molecular biology

  • insect defensins — See defensins …   Dictionary of molecular biology

  • Defensin — Monomeric and dimeric structures of human beta defensin HBD 2 Defensins are small cysteine rich cationic proteins found in both vertebrates and invertebrates. They have also been reported in plants.[1] …   Wikipedia

  • Alpha defensin — Mammalian defensin Structure of defensin HNP 3.[1] Identifiers Symbol Defensin 1 …   Wikipedia

  • Дефензины — Мономер(a) и димер(b) человеческого дефензина HBD2.[1] Дефензины (англ. defensin, от англ. defense защита) катионные пептиды иммунной системы, активные в отношении бактерий, грибков и многих оболочечных и без оболочечных вирусов. Состоят из 18 45 …   Википедия

  • Дефензин — Мономер(a) и димер(b) человеческого дефензина HBD2 …   Википедия

  • Beta defensin — Pfam box Symbol = Defensin beta Name = Beta defensin width =200 caption = Pfam= PF00711 InterPro= IPR001855 SMART= Prosite = SCOP = 1bnb TCDB = OPM family= 56 OPM protein= 1ut3 PDB=PDB3|1ijuC:33 68 PDB3|1kj5A:33 68 PDB3|1ijvB:33 68PDB3|1e4sA:33… …   Wikipedia

  • Paneth cell — Paneth cells provide host defense against microbes in the small intestine. They are functionally similar to neutrophils. When exposed to bacteria or bacterial antigens, Paneth cells secrete a number of antimicrobial molecules into the lumen of… …   Wikipedia

  • DEFB103A — Defensin, beta 103B PDB rendering based on 1kj6 …   Wikipedia

  • Cryptdin — is a term that refers to mammalian defensins of the alpha subfamily that are produced within the mouse small bowel. The word is a portmanteau that combines the terms crypt and defensin . Formally, in the scientific literature they are known as… …   Wikipedia

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