leucine zipper

leucine zipper
a stretch of amino acids consisting of four to seven leucine residues, each separated by six amino acids, occurring adjacent to a highly basic stretch of amino acids in some DNA-binding proteins. The configuration of the region is a helix, arranged such that leucine residues from two separate helices can interdigitate or interact to form dimers; the basic regions are arranged so as to recognize and bind specific DNA sequences.

Medical dictionary. 2011.

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  • leucine zipper — leucine zipper. См. лейциновая молния. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Leucine zipper — [ helical wheel diagram, of a leucine zipper, where d represent amino acid leucine , arranged with other amino acids on two parallel alpha helices.] A leucine zipper, aka leucine scissors [cite encyclopedia | editor = David M. Glick| encyclopedia …   Wikipedia

  • Leucine zipper — Domaine « leucine zipper » fixé à un brin d ADN ; les leucines sont colorées en rouge, on voit l interaction de leur radicaux isobutane. Un domaine leucine zipper (de l anglais, signifiant littéralement « fermeture éclair à… …   Wikipédia en Français

  • leucine zipper — Motif found in certain DNA binding proteins. In a region of around 35 amino acids, every seventh is a leucine. This facilitates dimerisation of two such proteins to form a functional transcription factor. Examples of proteins containing leucine… …   Dictionary of molecular biology

  • Basic Leucine Zipper Domain — CREB (top) ist ein Transkriptionsfaktor, der mit der bZip Domäne ein Dimer formt Die bZIP Domäne, auch Leucin Zipper genannt, ist eine Proteindomäne, die sich in vielen eukaryotischen DNA Bindeproteinen findet sowie der Dimerisierung von… …   Deutsch Wikipedia

  • Basic helix-loop-helix leucine zipper transcription factors — are, as their name indicates, transcription factors containing both Basic helix loop helix and leucine zipper motifs.An example is Microphthalmia associated transcription factor.External links* …   Wikipedia

  • basic leucine zipper — (= bZIP) Family of proteins having a basic region and a leucine zipper. The basic region is the DNA binding domain and the leucine zipper is involved in protein protein interactions to form homo or heterodimers. Includes AP 1, ATF and CREB… …   Dictionary of molecular biology

  • Leucine — L ou S(+) leucine D ou R( ) leucine Général …   Wikipédia en Français

  • Leucine-rich repeat — Pfam box Symbol = LRR 1 Name = width = caption = An example of a leucine rich repeat protein, a porcine ribonuclease inhibitor Pfam= PF00560 InterPro= IPR001611 SMART= Prosite = SCOP = 1bnh TCDB = OPM family= OPM protein= 1xwd PDB=PDB3|1ogqA:155… …   Wikipedia

  • zipper — See leucine zipper …   Dictionary of molecular biology

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