underfilling theory

underfilling theory
the theory that ascites associated with portal hypertension causes hypovolemia and so both a lowering of portal pressure and retention of sodium and water. The higher sodium concentration causes increases in the plasma volume and portal pressure, and the subsequent formation of ascites renews the cycle. See also overflow t.

Medical dictionary. 2011.

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  • overflow theory — a theory of ascites formation similar to the underfilling theory but proposing that the primary event is sodium and water retention resulting in portal hypertension; plasma volume expansion to the point of overflow from the hepatic sinusoids then …   Medical dictionary

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