cholestasis

cholestasis
See cholestasia.
- intrahepatic c. of pregnancy intrahepatic c. with centrilobular bile staining without inflammatory cells or proliferation of mesenchymal cells; clinically characterized by pruritus and/or icterus; of unknown cause but associated with high estrogen levels. SYN: c. of pregnancy, cholestatic hepatosis icterus gravidarum, recurrent jaundice of pregnancy.
- c. of pregnancy SYN: intrahepatic c. of pregnancy.

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cho·le·sta·sis .kō-lə-'stā-səs, .käl-ə- n, pl -sta·ses -'stā-.sēz a checking or failure of bile flow
cho·le·stat·ic .kō-lə-'stat-ik, .käl-ə- adj

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n.
failure of normal amounts of bile to reach the intestine, resulting in obstructive jaundice. The cause may be a mechanical block in the bile ducts, such as a stone (extrahepatic biliary obstruction), or liver disease, such as that caused by the drug chlorpromazine in some hypersensitive individuals (intrahepatic cholestasis); it may also occasionally occur in pregnancy. The symptoms are jaundice with dark urine, pale faeces, and usually itching (pruritus).

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cho·le·sta·sis (ko″lə-staґsis) [chole- + -stasis] stoppage or suppression of the flow of bile. cholestatic adj

Medical dictionary. 2011.

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  • cholestasis — Any condition in which the release of bile from the liver is blocked. The blockage can occur in the liver (intrahepatic cholestasis) or in the bile ducts (extrahepatic cholestasis) …   English dictionary of cancer terms

  • cholestasis — n. failure of normal amounts of bile to reach the intestine, resulting in obstructive jaundice. The cause may be a mechanical block in the bile ducts, such as a stone (extrahepatic biliary obstruction), or liver disease, such as that caused by… …   The new mediacal dictionary

  • cholestasis — noun a condition in which little or no bile is secreted or the flow of bile into the digestive tract is obstructed • Syn: ↑acholia • Hypernyms: ↑disorder, ↑upset * * * cholestatic /koh leuh stat ik, kol euh /, adj. /koh leuh stay sis, stas is,… …   Useful english dictionary

  • Cholestasis with peripheral pulmonary stenosis — Also known as arteriohepatic dysplasia or Alagille syndrome, this ia a genetic disorder characterized by yellowing of the skin (jaundice) in the newborn period, liver disease with cholestasis, peripheral pulmonic stenosis and unusual face.… …   Medical dictionary

  • cholestasis — noun (plural cholestases) Etymology: New Latin Date: circa 1935 a checking or failure of bile flow • cholestatic adjective …   New Collegiate Dictionary

  • cholestasis — cholestatic /koh leuh stat ik, kol euh /, adj. /koh leuh stay sis, stas is, kol euh /, n. Pathol. total or partial suppression of the flow of bile. [1930 35; CHOLE + STASIS] * * * …   Universalium

  • cholestasis — noun The suppression of the flow of bile caused by an obstruction associated with the liver …   Wiktionary

  • cholestasis — cho·le·sta·sis …   English syllables

  • cholestasis — cho•le•sta•sis [[t]ˌkoʊ ləˈsteɪ sɪs, ˈstæs ɪs, ˌkɒl ə [/t]] n. pat impairment of the flow of bile • Etymology: 1930–35 cho le•stat′ic ˈstæt ɪk adj …   From formal English to slang

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