ster·yl-sul·fa·tase (sterґəl sulґfə-tās) [EC] a microsomal enzyme of the hydrolase class that catalyzes the cleavage of the sulfate group from sulfated sterols. Deficiency of the enzyme, an X-linked trait, causes X-linked ichthyosis. Called also steroid sulfatase.

Medical dictionary. 2011.

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  • Sulfatase — Pfam box Symbol = Sulfatase Name = width =200 caption =Steryl sulfatase Pfam= PF00884 InterPro= IPR000917 SMART= PROSITE = PDOC00117 SCOP = 1auk TCDB = OPM family= 24 OPM protein= 1p49 PDB=PDB3|1fsu :43 486 PDB3|1hdhB:3 501 PDB3|1p49A:25… …   Wikipedia

  • Steroid sulfatase — (microsomal), isozyme S PDB rendering based on 1p49 …   Wikipedia

  • cholesterol sulfatase — cho·les·ter·ol sul·fa·tase (kə lesґtər ol sulґfə tās) steryl sulfatase …   Medical dictionary

  • steroid sulfatase — ster·oid sul·fa·tase (sterґoid sulґfə tās) steryl sulfatase …   Medical dictionary

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • arylsulfatase C — an arylsulfatase believed to be identical to steryl sulfatase …   Medical dictionary

  • X-linked ichthyosis — a chronic, X linked ichthyosis caused by deficiency of the microsomal enzyme steryl sulfatase as a result of mutation in the STS gene (locus: Xp22.32); it may be present at birth or appear in early infancy. It is characterized by prominent,… …   Medical dictionary

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