antigenic shift

antigenic shift
a sudden, major change in the antigenicity of a virus, seen especially in influenza viruses, resulting from the recombination of the genomes of two virus strains; it is associated with pandemics because hosts do not have immunity to the new strain. Cf. antigenic drift, under drift.

Medical dictionary. 2011.

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  • Antigenic shift — Not to be confused with antigenic drift or genetic drift. NIAID illustration of potential influenza antigenic shift Antigenic shift is the process by which two or more different strains of a virus, or strains of two or more different viruses …   Wikipedia

  • antigenic shift — A major change in the antigenic character of an organism that alters it to an antigenic strain unrecognized by host immune mechanisms …   Dictionary of microbiology

  • Antigenic drift — Antigenic driftcite journal author=D. J. D. Earn, J. Dushoff, S. A. Levin journal=Trends in Ecology and Evolution title=Ecology and Evolution of the Flu date=2002 volume=17 pages=334 340] [cite book author=A. W. Hampson chapter=Influenza virus… …   Wikipedia

  • antigenic drift — relatively minor changes in the antigenic structure of a virus strain, probably resulting from natural selection of virus variants circulating among an immune or partially immune population. Cf. antigenic shift, under shift …   Medical dictionary

  • shift — SYN: change. SEE ALSO: deviation. antigenic s. mutation, i.e., sudden change in molecular structure of RNA/DNA in microorganisms, especially viruses, which produces new strains; hosts previously exposed to other strains have little or no acquired …   Medical dictionary

  • Viral shift — A viral shift is the sudden emergence of a seemingly novel strain of a virus. It is a prerequisite viral condition for pandemics. An existing virus undergoes a change and becomes a pathogen, such as the constantly mutating A strain of influenza… …   Wikipedia

  • antigen shift — Abrupt change in surface antigens expressed by a species or variety of organisms. Usually seen in microorganisms where the change may allow escape from immune recognition. Antigenic drift is a more gradual change. See antigenic variation …   Dictionary of molecular biology

  • Influenza — Flu redirects here. For other uses, see Flu (disambiguation). This article is about the disease influenza. For the family of viruses that cause the disease, see Orthomyxoviridae. Influenza Classification …   Wikipedia

  • Influenza pandemic — Note: For information about the content, tone and sourcing of this article, please see the tags at the bottom of this page. An influenza pandemic is an epidemic of an influenza virus that spreads on a worldwide scale and infects a large… …   Wikipedia

  • Orthomyxoviridae — Virus classification Group: Group V (( )ssRNA) Order: Unassigned Family: Orthomyxoviridae …   Wikipedia

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