serglycin

serglycin
ser·gly·cin (ser-gliґsin) an intracellular proteoglycan, consisting of a 12-kD core with 24 serine-glycine repeats that are the attachment sites for about 15 glycosaminoglycans; it is expressed by leukocytes and binds histamine in secretory granules.

Medical dictionary. 2011.

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  • Degranulation — The degranulation process in a Mast cell. 1 = antigen; 2 = IgE; 3 = FcεRI; 4 = preformed mediators (histamine, proteases, chemokines, heparin); 5 = granules; 6 Mast cell; 7 newly formed mediators (prostaglandins, leukotrienes, t …   Wikipedia

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