ser·gly·cin (ser-gliґsin) an intracellular proteoglycan, consisting of a 12-kD core with 24 serine-glycine repeats that are the attachment sites for about 15 glycosaminoglycans; it is expressed by leukocytes and binds histamine in secretory granules.

Medical dictionary. 2011.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • serglycin — An intracellular proteoglycan, found particularly in the storage granules of connective tissue mast cells. The core protein consists of 153 amino acids with 24 serine glycine repeats between amino acids 89 and 137, hence the name. The serine… …   Dictionary of molecular biology

  • SRGN — Serglycin, also known as SRGN, is a human gene.cite web | title = Entrez Gene: SRGN serglycin| url = Cmd=ShowDetailView TermToSearch=5552| accessdate = ] PBB Summary section title = summary text =… …   Wikipedia

  • Platelet factor 4 — (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C X C motif) ligand 4 (CXCL4) . This chemokine is released from alpha granules of activated platelets during platelet aggregation, and promotes blood …   Wikipedia

  • Degranulation — The degranulation process in a Mast cell. 1 = antigen; 2 = IgE; 3 = FcεRI; 4 = preformed mediators (histamine, proteases, chemokines, heparin); 5 = granules; 6 Mast cell; 7 newly formed mediators (prostaglandins, leukotrienes, t …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”