cholestyramine resin

cholestyramine resin
[USP] a strongly basic anion exchange resin in the chloride form, consisting of styrene-divinylbenzene copolymer with quaternary ammonium functional groups, having an affinity for bile acids, which it binds into an insoluble complex that is excreted in the feces, resulting in elimination of bile acids from the enterohepatic circulation and in increased oxidation of cholesterol to bile acids; administered orally as adjunctive therapy to diet in the management of patients with elevated cholesterol due to familial hyperlipoproteinemia, type IIa (patients with pure hypercholesterolemia), for the relief of pruritus associated with cholestasis occurring in partial biliary obstruction, and to treat diarrhea due to excess bile acids in the colon.

Medical dictionary. 2011.

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  • cholestyramine resin — or cholestyramine [kō les′tir ə mēn΄, kō les tir′ə mēn΄] n. a powdery synthetic resin that binds with and prevents the reabsorption of bile acids, used to reduce cholesterol levels, relieve itching associated with jaundice, etc. * * * …   Universalium

  • cholestyramine resin — or cholestyramine [kō les′tir ə mēn΄, kō les tir′ə mēn΄] n. a powdery synthetic resin that binds with and prevents the reabsorption of bile acids, used to reduce cholesterol levels, relieve itching associated with jaundice, etc …   English World dictionary

  • cholestyramine — An anion exchange resin used to bind dietary cholesterol and hence prevent its systemic absorption. Used to treat hypercholesteremia. Can bind many acidic drugs in the gastrointestinal tract …   Medical dictionary

  • Cholestyramine — Clinical data Trade names Questran AHFS/Drugs.com …   Wikipedia

  • Resin, bile acid — Bile acid resins are substances that bind in the intestines with bile acids that contain cholesterol and are then eliminated in the stool. The major effect of bile acid resins is to lower LDL cholesterol by about 10 to 20 percent. Small doses of… …   Medical dictionary

  • resin — 1. An amorphous brittle substance consisting of the hardened secretion of a number of plants, probably derived from a volatile oil and similar to a stearoptene. 2. SYN: rosin. 3. A precipitate formed by the addition of water to certain tinctures …   Medical dictionary

  • cholestyramine — noun Etymology: chol + styrene + amine Date: circa 1962 a strongly basic synthetic resin that forms insoluble complexes with bile acids and has been used to lower cholesterol levels in hypercholesterolemic patients …   New Collegiate Dictionary

  • cholestyramine — ˌkōləˈstīrəˌmēn, kōˈlestirəˌmēn noun Etymology: chol + styrene + amine : a strongly basic ion exchange resin that forms insoluble complexes with bile acids and has been used to lower cholesterol levels in hypercholesterolemic patients …   Useful english dictionary

  • Ion exchange resin — An ion exchange resin is an insoluble matrix (or support structure) normally in the form of small (1 2 mm diameter) beads, usually white or yellowish, fabricated from an organic polymer substrate. The material has highly developed structure of… …   Wikipedia

  • Bile acid resin — Bile acid resins are substances that bind in the intestines with bile acids that contain cholesterol and are then eliminated in the stool. The major effect of bile acid resins is to lower LDL cholesterol by about 10 to 20 percent. Small doses of… …   Medical dictionary

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