LDL receptors

LDL receptors
low-density lipoprotein receptors specific receptors for low-density lipoprotein (LDL) found in coated pits on the surface of mammalian cells. The coated pits are internalized, forming coated vesicles from which LDL receptors are recycled back to the plasma membrane while LDL particles are transferred to lysosomes, where they are degraded, releasing free cholesterol, phospholipids, and amino acids. Genetic defects in LDL receptors are responsible for familial hypercholesterolemia.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • LDL receptor — The LDL Receptor is a mosaic protein that mediates the endocytosis of cholesterol rich LDL. It is a cell surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also… …   Wikipedia

  • LDL-receptor-related protein associated protein — Low density lipoprotein receptor related protein associated protein 1, also known as LRPAP1, is a human gene.cite web | title = Entrez Gene: LRPAP1 low density lipoprotein receptor related protein associated protein 1| url =… …   Wikipedia

  • low density lipoprotein receptor — (= LDL receptor) A cell surface protein that mediates the endocytosis of LDL by cells. Genetic defects in LDL receptors lead to abnormal serum levels of LDL and hypercholesterolaemia …   Dictionary of molecular biology

  • Familial hypercholesterolemia — Classification and external resources Xanthelasma palpebrarum, yellowish patches consisting of cholesterol deposits above the eyelids. These are more common in people with FH. ICD …   Wikipedia

  • Joseph L. Goldstein — Infobox Scientist name = Joseph L. Goldstein box width = image width =150px caption = Joseph L. Goldstein birth date = April 18, 1940 birth place = Kingstree, South Carolina death date = death place = residence = citizenship = nationality =… …   Wikipedia

  • Michael Stuart Brown — For other people named Michael Brown, see Michael Brown (disambiguation). Michael Stuart Brown Born April 13, 1941 ( …   Wikipedia

  • Браун, Майкл Стюарт — Майкл Стюарт Браун англ. Michael Stuart Brown …   Википедия

  • Браун, Майкл — Майкл Стюарт Браун (англ. Michael Stuart Brown; 13 апреля, 1941, Бруклин, Нью Йорк, США) известный американский врач и биохимик. За исследования наследственной гиперхолестеринемии и открытие рецептора липопротеинов низкой плотности вместе с… …   Википедия

  • Браун, Майкл С. — Майкл Стюарт Браун (англ. Michael Stuart Brown; 13 апреля, 1941, Бруклин, Нью Йорк, США) известный американский врач и биохимик. За исследования наследственной гиперхолестеринемии и открытие рецептора липопротеинов низкой плотности вместе с… …   Википедия

  • Браун Майкл — Майкл Стюарт Браун (англ. Michael Stuart Brown; 13 апреля, 1941, Бруклин, Нью Йорк, США) известный американский врач и биохимик. За исследования наследственной гиперхолестеринемии и открытие рецептора липопротеинов низкой плотности вместе с… …   Википедия

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”