therapeutic ratio

therapeutic ratio
the fraction of the minimal lethal dose of a drug that is therapeutically effective; called also curative r.

Medical dictionary. 2011.

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  • Therapeutic index — The therapeutic index (also known as therapeutic ratio), is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxic effects. Quantitatively, it is the ratio given by the toxic dose… …   Wikipedia

  • therapeutic index — n a measure of the relative desirability of a drug for the attaining of a particular medical end that is usu. expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures * * * the ratio of …   Medical dictionary

  • therapeutic index — noun : a measure of the relative desirability of a drug for attaining a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures * * * Pharm. the… …   Useful english dictionary

  • therapeutic index — Pharm. the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect. Also called margin of safety. [1925 30] * * * …   Universalium

  • therapeutic index — the ratio of a dose of a therapeutic agent that produces damage to normal cells to the dose that is necessary to have a defined level of anticancer activity. It indicates the relative efficacy of a treatment against tumours …   The new mediacal dictionary

  • therapeutic index — ther′apeu′tic in′dex n. pha the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect • Etymology: 1925–30 …   From formal English to slang

  • ratio — An expression of the relation of one quantity to another ( e.g., of a proportion or rate). SEE ALSO: index (2), quotient. [L. r. (ration ) a reckoning, reason, fr. reor, pp. ratus, to reckon, compute] absolute terminal innervation r. the number… …   Medical dictionary

  • therapeutic index — noun Date: 1926 a measure of the relative desirability of a drug for the attaining of a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures …   New Collegiate Dictionary

  • curative ratio — therapeutic r …   Medical dictionary

  • Incremental cost-effectiveness ratio — The incremental cost effectiveness ratio of an intervention in health care is a term used in cost effectiveness analysis in pharmacoeconomics. It is defined as the ratio of the change in costs of a therapeutic intervention (compared to the… …   Wikipedia

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