quinupristin

quinupristin
quin·u·pris·tin (kwin-uґpris-tin) a semisynthetic streptogramin antibacterial effective against a variety of gram-positive organisms, inhibiting the late phase of protein synthesis in the bacterial ribosome. It is used in conjunction with dalfopristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; administered intravenously.

Medical dictionary. 2011.

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  • Quinupristin/dalfopristin — drugbox IUPAC name = Quinupristin: N [(6 R ,9 S ,10 R ,13 S ,15a S ,18 R ,22 S ,24a S ) 22 [p (dimethylamino)benzyl] 6 ethyldocosahydro 10,23 dimethyl 5,8,12,15,17,21,24 heptaoxo 13 phenyl 18 [(3 S ) 3 quinuclidinylthio] methyl] 12 H pyrido [2,1… …   Wikipedia

  • quinupristin — noun A streptogramin antibiotic derived from pristinamycin …   Wiktionary

  • Streptogramin — Streptogramine bezeichnen eine Klasse an Antibiotika, die sich allesamt von Pristinamycin, einem Stoffwechselprodukt des Bakteriums Streptomyces pristinae spiralis ableiten. Ihnen ist gemein, dass sie die Proteinbiosynthese von Bakterien hemmen… …   Deutsch Wikipedia

  • Streptogramine — bezeichnen eine Klasse von Antibiotika, die sich allesamt von Pristinamycin, einem Stoffwechselprodukt des Bakteriums Streptomyces pristinae spiralis ableiten. Ihnen ist gemein, dass sie die Proteinbiosynthese von Bakterien hemmen und so deren… …   Deutsch Wikipedia

  • Streptogramin — Streptogramins are a class of antibiotics. They are a combination of Quinupristin and dalfopristin in a 30:70 ratio. Streptogramins are bactericidal. This class of antibiotics inhibit protein synthesis in a synergestic manner. Quinupristin binds… …   Wikipedia

  • Dalfopristin — Systematic (IUPAC) name (3R,4R,5E,10E,12E,14S,26R,26aS) 26 [[2 (diethylamino)ethyl]sulfonyl] 8,9,14,15,24,25,26,26a octahydro 14 hydroxy 3 isopropyl 4,12 dimethyl 3H 21,18 nitrilo 1H,22H pyrrolo[2,1 c] …   Wikipedia

  • Enterococcus — Taxobox color = lightgrey name = Enterococcus image width = 240px image caption = Enterococcus sp. infection in pulmonary tissue. regnum = Bacteria divisio = Firmicutes classis = Bacilli ordo = Lactobacillales familia = Enterococcaceae genus =… …   Wikipedia

  • Vancomycin-resistant Staphylococcus aureus — (VRSA) is a strain of Staphylococcus aureus that has become resistant to the glycopeptide antibiotic vancomycin. With the increase of staphylococcal resistance to methicillin, vancomycin (or teicoplanin) is often a treatment of choice in… …   Wikipedia

  • Pristinamycin — drugbox IUPAC name = CAS number = ATC prefix = J01 ATC suffix = FG01 PubChem = DrugBank = chemical formula = molecular weight = bioavailability = protein bound = metabolism = elimination half life = excretion = pregnancy AU = pregnancy US =… …   Wikipedia

  • Линезолид — …   Википедия

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