protein-glutamine γ-glutamyltransferase

protein-glutamine γ-glutamyltransferase
pro·tein-glu·ta·mine γ-glu·ta·myl·trans·fer·ase (proґtēn glooґtə-mēn gloo″tə-məl-transґfər-ās) [EC 2.3.2.13] an enzyme of the transferase class that creates crosslinks within and between fibrin molecules, transferring the glutamyl portion of glutamine side chains to the amino group of lysine side chains: protein-glutamine + lysine-protein = protein-glutamyl lysine-protein + NH3. The resultant polymerization of fibrin is an important part of blood clotting. It is the activated form of coagulation factor XIII (coagulation factor XIIIa). Called also transglutaminase.

Medical dictionary. 2011.

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