A 1,3-bis(phosphatidyl)glycerol found in many biomembranes with immunologic properties; used in serologic diagnosis of syphilis. When mixed with lecithin and cholesterol c. will combine with the Wassermann antibody but not with the treponema-immobilizing antibody. SYN: acetone-insoluble antigen, heart antigen.

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car·dio·lip·in .kärd-ē-ō-'lip-ən n a phospholipid obtained esp. from beef heart and used in combination with lecithin and cholesterol as an antigen in diagnostic blood tests for syphilis

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car·dio·lip·in (kahr″de-o-lipґin) [cardio-(1) + Gr. lipos fat] 1,3-diphosphatidylglycerol, a phospholipid occurring primarily in mitochondrial inner membranes and in bacterial plasma membranes. Cardiolipin is the main antigenic component of Wassermann-type antigens used in nontreponemal serologic tests for syphilis.

Medical dictionary. 2011.

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  • Cardiolipin — (alternate image) Cardiolip …   Wikipedia

  • Cardiolipin — Strukturformel der Cardiolipine. Die Reste R stehen für die Kohlenwasserstoffketten von Fettsäuren und können verschieden sein. Cardiolipin ist der Trivialname für Diphosphatidylglycerin (genauer: 1,3 bis(sn 3 phosphatidyl) sn glycerol), ein… …   Deutsch Wikipedia

  • cardiolipin — A diphosphatidyl glycerol that is found in the membrane of Treponema pallidum and is the antigen detected by the Wasserman test for syphilis …   Dictionary of molecular biology

  • cardiolipin — /kahr dee oh lip in/, n. Biochem. a lipid purified from bovine heart and used as an antigen for reacting with reagin, the Wassermann antibody, in the Wassermann diagnostic test for syphilis. [1942; CARDIO + LIP(ID) + IN2] * * * …   Universalium

  • cardiolipin — noun Any phospholipid having the structure of a bisphosphatidylglycerol present in the muscles of the heart …   Wiktionary

  • cardiolipin — car·dio·lip·in …   English syllables

  • cardiolipin — ˌ ̷ ̷ ̷ ̷ ̷ ̷ˈlipə̇n noun ( s) Etymology: cardi + lip + in : a phosphatide obtained especially from beef heart and used in antigens for diagnostic blood tests for syphilis * * * /kahr dee oh lip in/, n. Biochem. a lipid purified from bovine heart …   Useful english dictionary

  • Anti-cardiolipin antibodies — (ACA) are antibodies often directed against cardiolipin and found in several diseases including syphiliscite journal | author = Tringali GR, Julian AJ, Halbert WM | title = Effect of 2 mercaptoethanol treatment on anticardiolipin reactivity in… …   Wikipedia

  • CFT — cardiolipin flocculation test; clinical full time; complement fixation test; crystal field theory * * * CFT abbr complement fixation test * * * complement fixation test; see under fixation …   Medical dictionary

  • CLF — cardiolipin fluorescent [antibody]; ceroid lipofuscinosis; cholesterol lecithin flocculation …   Medical dictionary

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