- pharmacophore
- phar·ma·co·phore (fahrґmə-ko-for″) [pharmaco- + -phore] the group of atoms in a drug molecule which is responsible for the action of the compound.
Medical dictionary. 2011.
pharmacophore
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PHARMACOPHORE — Le terme de pharmocophore correspond à un concept théorique selon lequel un fragment moléculaire, plus ou moins important, serait déterminant pour l’activité biologique de la molécule à laquelle il appartient, de la même façon qu’un seul… … Encyclopédie Universelle
Pharmacophore — A pharmacophore was first defined by Paul Ehrlich in 1909 as a molecular framework that carries ( phoros ) the essential features responsible for a drug’s ( =pharmacon s ) biological activity (Ehrlich. Dtsch. Chem. Ges. 1909, 42: p.17). In 1977,… … Wikipedia
Pharmacophore — Un pharmacophore est constitué par une partie pharmacologiquement active d une molécule servant de modèle. Les pharmacophores sont donc des ensembles d atomes actifs utilisés dans la conception de médicaments. Le pharmacophore est une… … Wikipédia en Français
Pharmacophore discovery — is a means of lead discovery or lead optimization, used in drug development.External links*http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve db=PubMed list uids=12871063 dopt=Abstract … Wikipedia
pharmacophore — noun The molecular framework responsible for a drugs biological activity … Wiktionary
pharmacophore — … Useful english dictionary
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STRUCTURE ET FONCTION — L’étude de la relation entre les structures et les fonctions est au cœur même de la biologie. Cette relation s’exprime chez les êtres vivants par l’adaptation des premières aux secondes et pose une série de problèmes absolument fondamentaux,… … Encyclopédie Universelle
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