benzimidazole

benzimidazole
1. A ring system comprised of a benzene ring fused with an imidazole ring; occurs in nature as part of the vitamin B12 molecule. 2. A class of antihelmintic, often used to treat nematodes and cestodes.

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benz·imid·azole .ben-.zim-ə-'daz-.ōl, .ben-zə-'mid-ə-.zōl n a crystalline base C7H6N2 used esp. to inhibit the growth of various viruses, parasitic worms, and fungi also one of its derivatives

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ben·zi·mid·a·zole (ben″zĭ-midґə-zōl) a dicyclic compound comprising a benzene ring and an imidazole ring, occurring as part of the nucleotide portion of vitamin B12. Substituted benzimidazoles inhibit the action of H+/K+-ATPase at the secretory surface of the parietal cells, thus blocking the final step of gastric acid production, and are used as inhibitors of gastric acid secretion. Several benzimidazoles are used as anthelmintics.

Medical dictionary. 2011.

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  • benzimidazole — [bɛ̃zimidazɔl] n. m. ÉTYM. XXe, in Larousse 1932; de benz , et imidazole, de imide, et azole (de azote, et suff. sc. ole). ❖ ♦ Chim. Composé bicyclique aromatique, d …   Encyclopédie Universelle

  • Benzimidazole — Chembox new ImageFile = Benzimidazole chemical structure.png ImageSize = IUPACName = 1H benzimidazole OtherNames = Section1 = Chembox Identifiers CASNo = 51 17 2 PubChem = 5798 SMILES = c1cccc2ncnc12 Section2 = Chembox Properties C=7|H=6|N=2… …   Wikipedia

  • benzimidazole — benzimidazolas statusas T sritis chemija apibrėžtis Heterokciklinis junginys. formulė C₆H₄(NHCH=N) atitikmenys: angl. benzimidazole rus. бензимидазол …   Chemijos terminų aiškinamasis žodynas

  • benzimidazole — noun Etymology: International Scientific Vocabulary Date: 1912 a crystalline base C7H6N2 used especially to inhibit the growth of various viruses, parasitic worms, or fungi; also one of its derivatives …   New Collegiate Dictionary

  • benzimidazole — /ben zim i daz ohl, ben zeuh mid euh zohl /, n. Chem. a colorless crystalline compound, C7H6N2, used in organic synthesis. Also called benzoglyoxaline. [1925 30; BENZ + IMIDAZOLE] * * * …   Universalium

  • benzimidazole — noun A bicyclic heterocycle containing a benzene ring fused to that of imidazole; it is used as a pesticide …   Wiktionary

  • benzimidazole — benz·imidazole …   English syllables

  • benzimidazole — …   Useful english dictionary

  • Benzimidazole fungicide — Uses= Also called MBC fungicides, these were the first fungicides to be used to control eyespot in Europe from around 1974.Another use is against Sclerotinia in Oilseed Rape.Examples*Benomyl *Carbendazim *Thiophanate methyl …   Wikipedia

  • Discovery and development of proton pump inhibitors — Proton pump inhibitors (PPIs) block the gastric Hydrogen potassium ATPase (H+,K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid related diseases, including gastroesophageal reflux disease… …   Wikipedia

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