Medical dictionary. 2011.
Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… … Wikipedia
Aurora inhibitors — Aurora kinases regulate cell cycle transit from G2 through cytokinesis and, thus, are targets in cancer therapy [Andrews PD, Knatko E, Moore WJ, Swedlow JR. Mitotic mechanics: the auroras come into view. Current Opin in Cell Biol.(2003) 15:… … Wikipedia
Docetaxel — [1] Docetaxel Systematic (IUPAC) name 1,7β,10β trihydroxy 9 oxo 5β,20 epoxytax 11 ene 2α,4,13α triyl 4 acetate 2 benzoate 13 {(2R,3S) 3 [(tert butoxycarbonyl)amino] 2 hydroxy … Wikipedia
Paclitaxel — Systematic (IUPAC) name (2α,4α,5β,7β,10β,13α) 4,10 bis(acetyloxy) … Wikipedia
Vinblastine — Systematic (IUPAC) name dimethyl (2β,3β,4β,5α,12β,19α) 15 [(5S,9S) 5 ethyl 5 hydroxy 9 (methoxycarbonyl) Clinical data AHFS/ … Wikipedia
Demecolcine — Systematic (IUPAC) name (S) 1,2,3,10 Tetramethoxy 7 methylamino 6,7 dihydro 5H benzo[a]heptalen 9 one Clinical data Pregnancy cat … Wikipedia
Colchicine — Systematic (IUPAC) name N [(7S … Wikipedia
Colcemid — Used in cytogenetics, colcemid, also known as demecolcine, is related to colchicine but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and… … Wikipedia
Nocodazole — IUPAC name Methyl (5 [2 thienylcarbonyl] 1H benzimidazol 2 yl … Wikipedia
Nuclear transfer — is a form of cloning. The steps involve removing the DNA from an oocyte (unfertilized egg), and injecting the nucleus which contains the DNA to be cloned. In rare instances, the newly constructed cell will divide normally, replicating the new DNA … Wikipedia
