immunoperoxidase

immunoperoxidase
im·mu·no·per·ox·i·dase (im″u-no-pər-okґsĭ-das) pertaining to immunocytochemical methods using antibody coupled to the enzyme peroxidase to stain tissue constituents; frequently used to identify tissue antigens to aid diagnosis in surgical pathology.

Immunoperoxidase used to stain thyroid tissue for HLA class II (DR) antigen in the diagnosis of Graves disease. DR antigen is markedly expressed in thyroid glands from patients with autoimmune thyroid disease, but not in normal thyroid epithelial cells; its expression causes cells to stain brown with immunoperoxidase.


Medical dictionary. 2011.

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