α-ketoglutarate

α-ketoglutarate
A salt or ester of α-ketoglutaric acid.
- α-ketoglutarate dehydrogenase an enzyme that catalyzes the oxidative decarboxylation of 2-ketoglutaric acid to succinyldihydrolipoate; the succinyl group is later transferred to CoA and the reduced lipoate is oxidized by NAD+; a complex that is a part of the tricarboxylic acid cycle. SYN: 2-oxoglutarate dehydrogenase, α-ketoglutarate dehydrogenase complex.

Medical dictionary. 2011.

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