crossover hemoglobin

crossover hemoglobin
an abnormal hemoglobin that has a globin chain formed from parts of two chains that have undergone crossover, such as hemoglobin Lepore, h. anti-Lepore, and h. Kenya.

Medical dictionary. 2011.

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  • hemoglobin anti-Lepore — an abnormal crossover hemoglobin similar to hemoglobin Lepore but whose non α chains have fusion in the opposite configuration from those of hemoglobin Lepore (β chain portions at the N terminus and δ chain portions at the C… …   Medical dictionary

  • hemoglobin Kenya — an abnormal type of crossover hemoglobin in which the non α chain has a γ chain portion at the N terminus and a β chain portion at the C terminus, resulting in β thalassemia …   Medical dictionary

  • hemoglobin Lepore — any of several abnormal crossover hemoglobins having two normal α chains and two globin chains that have portions of a δ chain at the N terminus and portions of a β chain at the C terminus. Homozygous individuals have about 90 per… …   Medical dictionary

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