autocrine

autocrine
Denoting self-stimulation through cellular production of a factor and a specific receptor for it. [auto- + G. krino, to separate]

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au·to·crine -krin adj of, relating to, promoted by, or being a substance secreted by a cell and acting on surface receptors of the same cell <\autocrine stimulation of T cell growth> <\autocrine growth of some breast cancers (M. E. Lippman)> compare paracrine

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adj.
describing the production by a cell of substances, such as hormones or growth factor, that can influence the growth of the cell that produces them.

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au·to·crine (awґto-krin) denoting a mode of hormone action in which a hormone binds to receptors on and affects the function of the cell type that produced it.

Medical dictionary. 2011.

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  • Autocrine — Communication autocrine Le terme autocrine qualifie un messager chimique (hormone) qui agit sur la cellule même qui l a produit. Il s agit d un mode d expression dans le cadre des épithéliums glandulaires. Ce document provient de « Communication… …   Wikipédia en Français

  • autocrine — adjective Etymology: aut + crine (as in endocrine) Date: 1983 of, relating to, promoted by, or being a substance secreted by a cell and acting on surface receptors of the same cell < autocrine growth factors > < autocrine growth of a cancer >… …   New Collegiate Dictionary

  • autocrine — ˈȯd.ōkrin adjective Etymology: aut + crine (as in endocrine) : of, relating to, promoted by, or being a substance secreted by a cell and acting on surface receptors of the same cell autocrine stimulation of T cell growth autocrine growth of some …   Useful english dictionary

  • autocrine — Secretion of a substance, such as a growth factor, that stimulates the secretory cell itself. One route to independence of growth control is by autocrine growth factor production …   Dictionary of molecular biology

  • autocrine — adjective (of a hormone, neuropeptide... or about its effect or action) That acts on the cell that produced it. Vasopressin could be an autocrine hormone in the olfactory epithelium …   Wiktionary

  • Autocrine signalling — Autocrine signaling is a form of signaling in which a cell secretes a hormone, or chemical messenger (called the autocrine agent) that binds to autocrine receptors on the same cell, leading to changes in the cell. This can be contrasted with… …   Wikipedia

  • autocrine — [ ɔ:təʊkrʌɪn] adjective Biochemistry denoting or relating to a cell produced substance that has an effect on the cell by which it is secreted. Origin 1980s: from auto 1 + Gk krinein to separate …   English new terms dictionary

  • autocrine — au·to·crine …   English syllables

  • autocrine — adj. describing the production by a cell of substances, such as hormones or growth factors, that can influence the growth of the cell that produces them …   The new mediacal dictionary

  • autocrine growth factor — a polypeptide, produced endogenously by a cell free from usual external growth controls, that may act on its producer cell to cause malignant transformation …   Medical dictionary

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