autoantibody

autoantibody
Antibody occurring in response to antigenic constituents of the host's tissue against self antigen, and which reacts with the inciting tissue component.
- antiidiotype a. SYN: idiotype a..antiidiotype antibody.
- cold a. an a. that reacts at temperatures below 37°C.
- Donath-Landsteiner cold a. an a. of the IgG class responsible for paroxysmal cold hemoglobinuria; it is adsorbed to red cells only at temperatures of 20°C or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis. SYN: cold hemolysin.
- hemagglutinating cold a. a cold autoagglutinin.
- idiotype a. SYN: antiidiotype a..
- warm a. an a. that reacts optimally at 37°C.

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au·to·an·ti·body .ȯt-(.)ō-'ant-i-.bäd-ē n, pl -bod·ies an antibody active against a tissue constituent of the individual producing it

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n.
an antibody formed against one of the body's own components in an autoimmune disease.

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au·to·an·ti·body (aw″to-anґtĭ-bod″e) an antibody formed in response to, and reacting against, a self antigen (i.e., one of the individual's own normal tissue constituents).

Medical dictionary. 2011.

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Look at other dictionaries:

  • autoantibody — [ôt΄ō an′ti bäd΄ē] n. pl. autoantibodies an antibody that acts against the body s own molecules and tissues and may cause an autoimmune disorder …   English World dictionary

  • Autoantibody — An autoantibody is an antibody (a type of protein) manufactured by the immune system that is directed against one or more of the individual s own proteins. Many autoimmune diseases in humans, most notably lupus erythematosus, are caused by such… …   Wikipedia

  • autoantibody — /aw toh an ti bod ee, an tee /, n., pl. autoantibodies. Immunol. an antibody that an organism produces against any of its own tissues, cells, or cell components. [1905 10; AUTO 1 + ANTIBODY] * * * ▪ immunity       harmful antibody that attacks… …   Universalium

  • autoantibody — noun Date: circa 1910 an antibody active against a tissue constituent of the individual producing it …   New Collegiate Dictionary

  • autoantibody — Antibody that reacts with an antigen that is a normal component of the body. Obviously this can lead to some problems, and autoimmunity has been proposed as a causative factor in a number of diseases such as rheumatoid arthritis. See also… …   Dictionary of molecular biology

  • autoantibody — noun An antibody formed in response to an agent (autoantigen) produced by the organism itself …   Wiktionary

  • autoantibody — noun (plural autoantibodies) Physiology an antibody produced by an organism in response to a constituent of its own tissues …   English new terms dictionary

  • autoantibody — au·to·antibody …   English syllables

  • autoantibody — n. an antibody formed against one of the body s own components in an autoimmune disease …   The new mediacal dictionary

  • autoantibody — au•to•an•ti•bod•y [[t]ˌɔ toʊˈæn tɪˌbɒd i, ˈæn ti [/t]] n. pl. bod•ies imu an antibody that an organism produces against any of its own components • Etymology: 1905–10 …   From formal English to slang

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