chimeric gene

chimeric gene
an artificial gene constructed by juxtaposition of fragments of unrelated genes or other DNA, which may themselves have been altered in sequence.

Medical dictionary. 2011.

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  • Chimeric gene — Chimeric genes form through the combination of portions of one or more coding sequences to produce new genes. These mutations are distinct from fusion genes which merge whole gene sequences into a single reading frame and often retain their… …   Wikipedia

  • chimeric gene — An engineered gene, where a coding sequence is fused to promoter and/or other sequences derived from a different gene. Most genes used in transformation are chimeric. Synonym: fusion gene …   Glossary of Biotechnology

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  • Gene targeting — NOTOC Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to change an endogenous gene. The method can be used to delete a gene, remove exons, and introduce point …   Wikipedia

  • chimeric selectable marker gene — A gene that is constructed from parts of two or more different genes and allows the host cell to survive under conditions where it would otherwise die …   Glossary of Biotechnology

  • Abl gene — The abl gene is associated with chronic myelogenous leukemia (CML). The abl gene is located on the 9th chromosome. In CML, the gene is activated by being translocated within the bcr (breakpoint cluster region) gene on chromosome 22. This new… …   Wikipedia

  • TFG (gene) — TRK fused gene, also known as TFG, is a human gene.cite web | title = Entrez Gene: TFG TRK fused gene| url = Cmd=ShowDetailView TermToSearch=10342| accessdate = ] PBB Summary section title =… …   Wikipedia

  • fusion gene — See: chimeric gene …   Glossary of Biotechnology

  • marker gene — Gene that confers some readily detectable phenotype on cells carrying the gene, either in culture, or in transgenic or chimeric organisms. Gene could be an enzymic reporter gene, a selectable marker conferring antibiotic resistance, or a cell… …   Dictionary of molecular biology

  • HLF (gene) — Hepatic leukemia factor, also known as HLF, is a human gene.cite web | title = Entrez Gene: HLF hepatic leukemia factor| url = Cmd=ShowDetailView TermToSearch=3131| accessdate = ] PBB Summary… …   Wikipedia

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