keratin filaments

keratin filaments
intermediate filaments composed of cytokeratins; they are usually heteropolymers formed from one acidic and one basic cytokeratin and are present in most epithelial cells. The cytokeratin composition varies in different types, states, and degrees of differentiation of the epithelia and has been used as an immunohistochemical marker. These filaments form a cytoskeletal framework, anchoring other elements and inserting into sites of cell-to-cell contact and are thus tonofilaments (q.v.).

Medical dictionary. 2011.

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