necrolytic migratory erythema

necrolytic migratory erythema
a generalized, symmetrical, scaling, eczematous dermatitis with migratory necrolysis of the upper epidermis, liquefaction of the granular layer, and formation of clefts in the subcorneal region. There is flaccid bulla formation, erosion, crusting, and healing with hyperpigmentation. It may be seen on the face, abdominal or groin area, or lower limbs. There is often an associated glucagonoma. See also glucagonoma syndrome, under syndrome.

Medical dictionary. 2011.

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