reference dose

reference dose
an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.

Medical dictionary. 2011.

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  • Reference dose — A reference dose is the United States Environmental Protection Agency s maximum acceptable oral dose of a toxic substance. Reference doses are most commonly determined for pesticides. The EPA defines an oral reference dose (abbreviated RfD) as:… …   Wikipedia

  • Dose — means quantity in the following fields: In nutrition, medicine, and toxicology: Dose (biochemistry), the quantity of something that may be eaten by or administered to an organism, or that an organism may be exposed to Medicine and toxicology… …   Wikipedia

  • Dose Efficace — En physique nucléaire, la dose efficace est une grandeur physique mesurant l impact sur les tissus biologiques d une exposition à un rayonnement ionisant, notamment à une source de radioactivité. Il se définit comme la dose absorbée, à savoir l… …   Wikipédia en Français

  • Dose — Dose, v. t. [imp. & p. p. {Dosed}; p. pr. & vb. n. {dosing}.] [Cf. F. doser. See {Dose}, n.] 1. To proportion properly (a medicine), with reference to the patient or the disease; to form into suitable doses. [1913 Webster] 2. To give doses to; to …   The Collaborative International Dictionary of English

  • reference — see IDEA OF REFERENCE ref·er·ence ref (ə )rən(t)s adj of known potency and used as a standard in the biological assay of a sample of the same drug of unknown strength <a dose of reference cod liver oil> …   Medical dictionary

  • Dose efficace — En radioprotection, la dose efficace est une grandeur physique mesurant l impact sur les tissus biologiques d une exposition à un rayonnement ionisant, notamment à une source de radioactivité. Il se définit comme la dose absorbée, à savoir l… …   Wikipédia en Français

  • Équivalent de dose efficace — Dose efficace En physique nucléaire, la dose efficace est une grandeur physique mesurant l impact sur les tissus biologiques d une exposition à un rayonnement ionisant, notamment à une source de radioactivité. Il se définit comme la dose absorbée …   Wikipédia en Français

  • Median lethal dose — This article is about the toxicological term. For the album by Mudvayne, see L.D. 50 (album). For other uses, see LD50 (disambiguation). In toxicology, the median lethal dose, LD50 (abbreviation for “Lethal Dose, 50%”), LC50 (Lethal Concentration …   Wikipedia

  • Physicians' Desk Reference — The Physicians Desk Reference ( PDR ) is a commercially published compilation of manufacturers prescribing information (package insert) on prescription drugs, updated annually. While designed to provide physicians with the full legally mandated… …   Wikipedia

  • Canadian National Calibration Reference Centre — The National Calibration Reference Centre for Bioassay and In Vivo Monitoring (NCRC) is administered by the Radiation Protection Bureau of the Canadian Federal Department of Health. It was created in 1982 through a Memorandum of Understanding… …   Wikipedia

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