immunoproliferative small intestine disease

immunoproliferative small intestine disease
(IPSID) the gastrointestinal form of alpha chain disease, characterized by diarrhea, malabsorption, abdominal pain, clubbing, plasma cell infiltration of the lamina propria of the small bowel, and presence of an abnormal alpha heavy chain fragment in the serum; it frequently evolves into primary malignant lymphoma. Called also Mediterranean lymphoma.

Medical dictionary. 2011.

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