heparin cofactor II

heparin cofactor II
a member of the serpin group, a single-chain glycoprotein, Mr 65,000, that inhibits thrombin. It resembles antithrombin III in being markedly stimulated by heparin; it differs in that it binds and is activated by dermatan sulfate and in that it does not inhibit any other activated coagulation factors.

Medical dictionary. 2011.

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