- An acid-stable semisynthetic penicillin derived from 6-aminopenicillanic acid; it has a broader spectrum of antimicrobial action than penicillin G, inhibits the growth of Gram-positive and Gram-negative bacteria, and is not resistant to penicillinase; also available as a. sodium and a. trihydrate. SYN: d(-)-α-aminobenzylpenicillin.
* * *am·pi·cil·lin .am-pə-'sil-ən n a penicillin C16H19N3O4S that is effective against gram-negative and gram-positive bacteria and is used in anhydrous forms, as the trihydrate, or as the sodium salt to treat various infections of the urinary, respiratory, and intestinal tracts see penbritin
* * *n.an antibiotic used to treat a variety of infections, including those of the urinary, respiratory, biliary, and intestinal tracts. It is inactivated by penicillinase and therefore cannot be used against organisms producing this enzyme. It is given by mouth or injection; side-effects include nausea, vomiting, and diarrhoea, and some allergic reactions may occur. Trade names: Penbritin, Rimacillin.
* * *am·pi·cil·lin (am″pĭ-silґin) [USP] a semisynthetic, acid-resistant, penicillinase-sensitive penicillin of the aminopenicillin group, effective against a broad spectrum of gram-positive and gram-negative bacteria, used in the treatment of infections caused by susceptible organisms; administered orally.
Medical dictionary. 2011.