Any one of the genetically determined antigenic differences within a given class of immunoglobulin that occur among members of the same species. SEE ALSO: antibody. SYN: allotypic marker. [allo- + G. typos, model]
- Gm allotypes (al′lo-tips) refers to human immunoglobulin gamma heavy chains that express different Gm allotypic determinants (antigens). Each of the 25 different Gm allotypes is the product of genes within the constant regions of the human gamma heavy chain.
- InV allotypes (al′lo-tips) SYN: Km allotypes.
- Km allotypes (al′lo-tip) refers to human kappa immunoglobulin light chains that express different Km allotypic determinants (antigens). SYN: InV allotypes.

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al·lo·type 'al-ə-.tīp n an alloantigen that is part of a plasma protein (as an antibody) compare IDIOTYPE, ISOTYPE
al·lo·typ·ic .al-ə-'tip-ik adj
al·lo·typ·i·cal·ly -i-k(ə-)lē adv
al·lo·typy 'al-ə-.tī-pē n, pl -typ·ies

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al·lo·type (alґo-tīp) [allo- + type] any of several allelic variants of a protein that are characterized by antigenic differences (allotypic markers), especially allelic variants of immunoglobulin heavy and light chains. Cf. isotype and idiotype.

Medical dictionary. 2011.

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  • allotype — [a(l)lɔtip] n. m. ÉTYM. Mil. XXe (1974, in la Clé des mots); de allo , et type. ❖ ♦ Biol. Se dit de cellules dont les protéines ont une spécificité antigénique variable dans une même espèce …   Encyclopédie Universelle

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  • Allotype — Un allotype (du grec « autre forme ») est une particularité permettant de différencier des individus au sein d une même espèce. Cette particularité est donc un phénotype dû à la présence, dans le génome de l individu, de l allèle… …   Wikipédia en Français

  • allotype — noun a) A specimen that exemplifies the opposite sex of the holotype. b) An immunoglobulin allotype is the allele of the antibody chains found in the individual …   Wiktionary

  • allotype — noun Date: 1960 an alloantigen that is part of a plasma protein (as an antibody) • allotypic adjective • allotypically adverb • allotypy noun …   New Collegiate Dictionary

  • allotype — a paratype of opposite sex to the holotype and originally designated by the author, a term not regulated by the International Code of Zoological Nomenclature …   Dictionary of ichthyology

  • allotype — n. [Gr. allos, other; typos, type] A paratype of the opposite sex to the holotype …   Dictionary of invertebrate zoology

  • allotype — Allelic variants of antigenic determinant(s) found on antibody chains of some, but not all, members of a species, which are inherited as simple Mendelian traits …   Dictionary of microbiology

  • allotype — Products of one or more alleles that can be detected as inherited variants of a particular molecule. Usually the usage is restricted to those immunoglobulins that can be separately detected antigenically. See also idiotype. In humans light chain… …   Dictionary of molecular biology

  • allotype — allotypic /al euh tip ik/, adj. allotypically, adv. allotypy /al euh tuy pee/, n. /al euh tuyp /, n. 1. Biol. a type specimen of the sex opposite to that of the holotype. 2. Immunol. an antibody of a given class having certain molecular sites… …   Universalium

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