Aldosterone antagonist — refers to drugs which antagonise the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure. Spironolactone, the… … Wikipedia
Aldosterone — Chembox new ImageFile = Aldosterone 2D skeletal.svg ImageSize = IUPACName = 11β,21 dihydroxy 3,20 dioxopregn 4 en 18 al OtherNames = Section1 = Chembox Identifiers CASNo = 52 39 1 PubChem = 5839 SMILES = C [C@] 12CCC(=O)C=C1CC [C@@H] 3 [C@@H] 2… … Wikipedia
Antagonist — In biochemistry, an antagonist acts against and blocks an action. For example, insulin lowers the level of glucose (sugar) in the blood, whereas another hormone called glucagon raises it; therefore, insulin and glucagon are antagonists. An… … Medical dictionary
Système rénine-angiotensine-aldostérone — Schéma du système rénine angiotensine aldostérone dans sa complexité … Wikipédia en Français
Cholecystokinin antagonist — A Cholecystokinin antagonist is a specific type of receptor antagonist which blocks the receptor sites for the peptide hormone Cholecystokinin (CCK). There are two subtypes of this receptor known at present, defined as CCKA and CCKB (also called… … Wikipedia
Angiotensin II receptor antagonist — Angiotensin II receptor antagonists, also known as angiotensin receptor blockers (ARBs), AT1 receptor antagonists or sartans, are a group of pharmaceuticals which modulate the renin angiotensin aldosterone system. Their main use is in… … Wikipedia
Corticotropin releasing hormone antagonist — A Corticotropin releasing hormone antagonist is a specific type of receptor antagonist which blocks the receptor sites for Corticotropin releasing hormone (also known as Corticotropin releasing factor (CRF)), blocking therefore the consequent… … Wikipedia
angiotensin receptor antagonist — angiotensin II receptor antagonist any of a class of antihypertensive agents that block the vasoconstrictor and aldosterone secreting effects of angiotensin II by competitive binding with angiotensin receptors. Called also angiotensin receptor or … Medical dictionary
spironolactone — Aldosterone antagonist: diuretic; used to treat low renin hypertension, and Conn s syndrome (in which there is overproduction of aldesterone) … Dictionary of molecular biology
Spironolactone — Systematic (IUPAC) name 7α Acetylthio 3 oxo 17α pregn 4 ene 21,17 carbolactone OR (1 S,2R,2 R,9 R,10 R,11 S,15 S) 9 (acetylsulfanyl) 2 ,15 dimethylspiro[oxolane 2,14 tetracyclo[8.7.0.0 … Wikipedia