filaggrin

filaggrin
A major protein of the keratohyalin granule, composed mostly of l-histidyl, lysyl, and arginyl residues (stratum corneum basic proteins). It aggregates keratin intermediate filaments and promotes disulfide bond formation. [filament + aggregating]

* * *

fil·ag·grin (fil-agґrin) a protein that is synthesized in the granular layer of the epidermis and aggregates intermediate filaments of keratin by promoting formation of disulfide bonds.

Medical dictionary. 2011.

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